Journal: European journal of pharmacology

Article Title: Effects of garlic oil and diallyl trisulfide on glycemic control in diabetic rats.

doi: 10.1016/j.ejphar.2005.04.031

Figure Lengend Snippet: Fig. 1. Effect of treatment with garlic oil or diallyl trisulfide on the decay in plasma glucose concentrations in response to a bolus injection of insulin as a function of time (A) and the first-order rate constant for the disappearance rate of glucose in plasma (KITT) after the insulin bolus (B). An insulin bolus (1 U/kg body weight) was administered intraperitoneally on day 10 after the induction of diabetes. The change in plasma glucose concentrations is presented as the percentage of the glucose value at time zero. Data are meansTS.D. for six rats per group. *Significant difference between the control group and the DM group ( P <0.05). #Significant difference between the garlic oil- or diallyl trisulfide-treated group and the DM group ( P <0.05).

Article Snippet: Three days after the injection, the diabetic animals were randomly assigned to three groups and received by gavage garlic oil (100 mg/kg body weight), diallyl trisulfide (40 mg/kg body weight; LKT Laboratories, Inc., St. Paul, MN), or the vehicle (corn oil; 2 ml/kg body weight) every other day for 3 weeks.

Techniques: Clinical Proteomics, Injection, Control

Journal: European journal of pharmacology

Article Title: Effects of garlic oil and diallyl trisulfide on glycemic control in diabetic rats.

doi: 10.1016/j.ejphar.2005.04.031

Figure Lengend Snippet: Fig. 2. Effect of treatment of diabetic rats with garlic oil or diallyl trisulfide on the concentration of plasma glucose as a function of time (A), the increment in plasma glucose (B), the concentration of plasma insulin as a function of time (C), and the increment in plasma insulin (D) in response to an oral glucose bolus. A glucose bolus (1 g/kg body weight) was administered orally on day 17 after the induction of diabetes. Glucose was measured in plasma samples from the tail vein. The data in (B) and (D) are calculated from the areas under the curve of (A) and (C), respectively. Data are meansTS.D. for six rats per group. *Significant difference between the control group and the DM group ( P <0.05). #Significant difference between the garlic oil- or diallyl trisulfide-treated group and the DM group ( P <0.05).

Article Snippet: Three days after the injection, the diabetic animals were randomly assigned to three groups and received by gavage garlic oil (100 mg/kg body weight), diallyl trisulfide (40 mg/kg body weight; LKT Laboratories, Inc., St. Paul, MN), or the vehicle (corn oil; 2 ml/kg body weight) every other day for 3 weeks.

Techniques: Concentration Assay, Clinical Proteomics, Control

Journal: European journal of pharmacology

Article Title: Effects of garlic oil and diallyl trisulfide on glycemic control in diabetic rats.

doi: 10.1016/j.ejphar.2005.04.031

Figure Lengend Snippet: Fig. 3. Effect of treatment of diabetic rats with garlic oil or diallyl trisulfide on rates of glucose conversion to lactate (A), glycogen (B), and carbon dioxide (C) in the presence of 10 or 100 AU/ml of insulin. Muscles were isolated from diabetic rats or normal control rats. Data are meansTS.D. for six rats per group. *Significant difference between the control group and the DM group ( P <0.05). #Significant difference between the garlic oil-treated or diallyl trisulfide-treated group and the DM group ( P <0.05).

Article Snippet: Three days after the injection, the diabetic animals were randomly assigned to three groups and received by gavage garlic oil (100 mg/kg body weight), diallyl trisulfide (40 mg/kg body weight; LKT Laboratories, Inc., St. Paul, MN), or the vehicle (corn oil; 2 ml/kg body weight) every other day for 3 weeks.

Techniques: Muscles, Isolation, Control